Alzheimer’s amyloid-β drug hangs in the balance
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منابع مشابه
As the Antarctic Ice Pack Recedes, a Fragile Ecosystem Hangs in the Balance
Feature Open access, freely available online H arrowing tales of starvation and endurance epitomize Antarctica's " heroic age, " when men equipped with little more than fortitude struggled against a landscape seemingly designed to thwart their intentions. A menacing sea ice fi gures prominently in these improbable survival stories. Daunting to early-20th-century explorers—trapping (and ultimate...
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Background: Multiple sclerosis (MS) is one of the most common autoimmune diseases in adults that cause disability in patients. Different studies were conducted on more rapid diagnosis of the disease such as measuring serum or cerebrospinal fluid (CSF) contents. Objectives: The current study aimed at measuring amyloid β (Aβ) serum levels in patients with relapsing-remitting MS. Mater...
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An improved production and purification method for Alzheimer's disease related methionine-modified amyloid-β 1-40 and 1-42 peptides is proposed, taking advantage of the formation of inclusion body in Escherichia coli. A Thioflavin-S assay was set-up to evaluate inclusion body formation during growth and optimize culture conditions for amyloid-β peptides production. A simple and fast purificatio...
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ژورنال
عنوان ژورنال: Nature Aging
سال: 2021
ISSN: 2662-8465
DOI: 10.1038/s43587-021-00059-x